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| * '''Description:''' transcriptional regulator required for the expression of [[SigK]]-dependent late spore coat genes <br/><br/>
| | {{#bank: GerE}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''gerE''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator (LuxR-FixJ family)
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| |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of [[SigK]]-dependent gene expression
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 8 kDa, 9.635
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 222 bp, 74 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ysmB]]'', ''[[ysmA]]''
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| |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14801]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| |colspan="2" | '''Genetic context''' <br/> [[Image:gerE_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |}
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| __TOC__
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| <br/><br/>
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU28410
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| ===Phenotypes of a mutant ===
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/gerE.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10355]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:''' LuxR-FixJ family of transcription regulators
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| * '''Paralogous protein(s):'''
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| === Genes controlled by GerE ===
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| ''[[lipC]],'' ''[[surC]]''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''Interactions:'''
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| * '''Localization:'''
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| === Database entries ===
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| * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1FSE 1FSE]
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P11470 P11470]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU28410]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''gerE'' {{PubMed|3114423}}
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| * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|15699190}}
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| * '''Regulation:'''
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| ** expressed late during sporulation in the mother cell ([[SigK]], [[SpoIIID]]) {{PubMed|15699190,7896717}}
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| * '''Regulatory mechanism:'''
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| ** [[SpoIIID]]: transcription activation {{PubMed|7896717}}
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| * '''Additional information:'''
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| * [[Arthur Aronson]], Purdue University, West Lafayette, USA [http://wwwdev.gradschool.purdue.edu/PULSe/faculty.cfm?fid=5&range=0 homepage]
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| * [[Charles Moran]], Emory University, NC, USA [http://www.microbiology.emory.edu/moran_c.html homepage]
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| =Your additional remarks=
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| =References=
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| <pubmed>7519271,2474075,11418558,10400595,7592393,11741866,7592342,3135411,9852018,1691789,15383836,11150673,1518043,7814326,14523132,12031481,11418558, 3114423 7896717 11243786 17890309 15470121 </pubmed>
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| [[Category:Protein-coding genes]]
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