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* '''Description:''' formylmethionine deformylase <br/><br/>
{{#bank: DefA}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''def''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yloK ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || formylmethionine deformylase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || translation
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 4.731 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 480 bp, 160 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[priA]]'', ''[[fmt]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13445&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:def_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|}
__TOC__
<br/><br/>
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU15720
===Phenotypes of a mutant ===
=== Database entries ===
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11933]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:''' Formyl-L-methionyl peptide + H<sub>2</sub>O = formate + methionyl peptide (according to Swiss-Prot)
* '''Protein family:''' polypeptide deformylase family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''Interactions:'''
* '''Localization:'''
=== Database entries ===
* '''Structure:'''
* '''UniProt:''' [http://www.uniprot.org/uniprot/P94462 P94462]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU15720]
* '''E.C. number:''' [http://www.expasy.org/enzyme/3.5.1.88 3.5.1.88]
=== Additional information===
=Expression and regulation=
* '''Operon:''' ''[[def]]-[[fmt]]-[[yloM]]'' [http://www.ncbi.nlm.nih.gov/pubmed/16964327?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum PubMed]
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/pubmed/16964327?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum PubMed]
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>16964327,11429456,,12627383, </pubmed>
[[Category:Protein-coding genes]]

Latest revision as of 12:30, 20 August 2013