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* '''Description:''' acyl-carrier protein synthase <br/><br/>
{{#bank: AcpS}}


{| align="right" border="1" cellpadding="2"
|-
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''acpS''
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ydcB ''
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || acyl-carrier protein synthase
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || fatty acid biosynthesis
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 13 kDa, 9.915 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 363 bp, 121 aa
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydcA]]'', ''[[ydcC]]''
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12269&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
|-
|colspan="2" | '''Genetic context''' <br/> [[Image:acpS_context.gif]]
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|}
__TOC__
<br/><br/>
=The gene=
=== Basic information ===
* '''Locus tag:''' BSU04620
===Phenotypes of a mutant ===
essential [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed]
=== Database entries ===
* '''DBTBS entry:''' no entry
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12089]
=== Additional information===
=The protein=
=== Basic information/ Evolution ===
* '''Catalyzed reaction/ biological activity:''' CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein] (according to Swiss-Prot)
* '''Protein family:''' AcpS family (according to Swiss-Prot)
* '''Paralogous protein(s):'''
=== Extended information on the protein ===
* '''Kinetic information:'''
* '''Domains:'''
* '''Modification:'''
* '''Cofactor(s):'''
* '''Effectors of protein activity:'''
* '''Interactions:''' [[AcpA]]-[[AcpS]]
* '''Localization:''' cytoplasm (according to Swiss-Prot)
=== Database entries ===
* '''Structure:'''
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P96618 P96618]
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU04620]
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.8.7 2.7.8.7]
=== Additional information===
=Expression and regulation=
* '''Operon:'''
* '''[[Sigma factor]]:'''
* '''Regulation:'''
* '''Regulatory mechanism:'''
* '''Additional information:'''
=Biological materials =
* '''Mutant:'''
* '''Expression vector:'''
       
* '''lacZ fusion:'''
* '''GFP fusion:'''
* '''two-hybrid system:'''
* '''Antibody:'''
=Labs working on this gene/protein=
=Your additional remarks=
=References=
<pubmed>11489886,15955059,10997907,11867633,, </pubmed>

Latest revision as of 13:02, 2 April 2014