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{{#bank: nrdI}}
* '''Description:''' flavodoxin, ribonucleoside-diphosphate reductase <br/><br/>
* '''Description:''' flavodoxin, ribonucleoside-diphosphate reductase <br/><br/>


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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of deoxyribonucleoside triphosphates
|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of deoxyribonucleoside triphosphates
|-
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]'''
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17370 nrdI]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=NrdI NrdI]
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=nrdI nrdI]'''
|-
|-
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 8.58   
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 14 kDa, 8.58   
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|colspan="2" | '''Genetic context''' <br/> [[Image:ymaA_context.gif]]
|colspan="2" | '''Genetic context''' <br/> [[Image:ymaA_context.gif]]
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
|-
|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nrdI_1868617_1869009_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:nrdI_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU17370]]
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|-
|}
|}


__TOC__
__TOC__
 
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= [[Categories]] containing this gene/protein =
= [[Categories]] containing this gene/protein =
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=== Database entries ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17370&redirect=T BSU17370]


* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/nrdIEF-ymaB.html]
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/nrdIEF-ymaB.html]
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* '''[[SubtInteract|Interactions]]:'''
* '''[[SubtInteract|Interactions]]:'''
** [[NrdI]]-[[NrdF]] {{PubMed|23402532}}


* '''[[Localization]]:'''
* '''[[Localization]]:'''


=== Database entries ===
=== Database entries ===
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU17370&redirect=T BSU17370]


* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1RLJ 1RLJ]
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1RLJ 1RLJ]
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nrdI_1868617_1869009_1 nrdI] {{PubMed|22383849}}
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nrdI_1868617_1869009_1 nrdI] {{PubMed|22383849}}


* '''Sigma factor:''' [[SigA]] {{PubMed|16885274}}
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|16885274}}


* '''Regulation:'''  
* '''Regulation:'''  
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<pubmed> 17229208 </pubmed>
<pubmed> 17229208 </pubmed>
==Original Publications==
==Original Publications==
<pubmed>16885274,8969495, 12682299 ,20525796 </pubmed>
'''Additional publications:''' {{PubMed|23402532}}
<pubmed>16885274,8969495, 12682299 ,20525796</pubmed>


[[Category:Protein-coding genes]]
[[Category:Protein-coding genes]]

Latest revision as of 09:54, 7 December 2016

nrdI

  • Description: flavodoxin, ribonucleoside-diphosphate reductase

Gene name nrdI
Synonyms ymaA
Essential yes PubMed
Product ribonucleoside-diphosphate reductase
Function synthesis of deoxyribonucleoside triphosphates
Gene expression levels in SubtiExpress: nrdI
Interactions involving this protein in SubtInteract: NrdI
Metabolic function and regulation of this protein in SubtiPathways:
nrdI
MW, pI 14 kDa, 8.58
Gene length, protein length 390 bp, 130 aa
Immediate neighbours ymzA, nrdE
Gene sequence (+200bp) Protein sequence
Genetic context
This image was kindly provided by SubtiList
Expression at a glance   PubMed















Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, essential genes

This gene is a member of the following regulons

ResD regulon

The gene

Basic information

  • Locus tag: BSU17370

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: nrdI family (according to Swiss-Prot)
  • Paralogous protein(s): YosM

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

<pubmed> 17229208 </pubmed>

Original Publications

Additional publications: PubMed <pubmed>16885274,8969495, 12682299 ,20525796</pubmed>

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