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| * '''Description:''' capsular polyglutamate biosynthesis <br/><br/>
| | {{#bank: CapC}} |
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| {| align="right" border="1" cellpadding="2"
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| |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| |''capC''
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| |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ywtA, pgsC''
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| |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| |style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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| |style="background:#ABCDEF;" align="center"|'''Function''' || capsule synthesis
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| |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 9.672
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| |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 447 bp, 149 aa
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| |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[capA]]'', ''[[capB]]''
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| |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15606]+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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| |colspan="2" | '''Genetic context''' <br/> [[Image:ywtA_context.gif]]
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| <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| |-
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| |}
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| __TOC__
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| <br/><br/>
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| = [[Categories]] containing this gene/protein =
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| {{SubtiWiki category|[[capsule biosynthesis and degradation]]}}
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| = This gene is a member of the following [[regulons]] =
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| {{SubtiWiki regulon|[[DegU regulon]]}}
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| =The gene=
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| === Basic information ===
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| * '''Locus tag:''' BSU35890
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| ===Phenotypes of a mutant ===
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| no synthesis of the poly-gamma-glutamate capsule [http://www.ncbi.nlm.nih.gov/sites/entrez/11751809 PubMed]
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| === Database entries ===
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| * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ywsC-ywtABC.html]
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| * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG12532]
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| === Additional information===
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| =The protein=
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| === Basic information/ Evolution ===
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| * '''Catalyzed reaction/ biological activity:'''
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| * '''Protein family:'''
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| * '''Paralogous protein(s):'''
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| === Extended information on the protein ===
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| * '''Kinetic information:'''
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| * '''Domains:'''
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| * '''Modification:'''
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| * '''Cofactor(s):'''
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| * '''Effectors of protein activity:'''
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| * '''[[SubtInteract|Interactions]]:'''
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| * '''[[Localization]]:'''
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| === Database entries ===
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| * '''Structure:'''
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| * '''UniProt:''' [http://www.uniprot.org/uniprot/P96737 P96737]
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| * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU35890]
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| * '''E.C. number:'''
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| === Additional information===
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| =Expression and regulation=
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| * '''Operon:''' ''[[capB]]-[[capC]]-[[capA]]-[[capE]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/11751809 PubMed]
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| * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pgsC_3698982_3699431_-1 capC] {{PubMed|22383849}}
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| * '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19420703 PubMed]
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| * '''Regulation:'''
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| * '''Regulatory mechanism:''' activated by [[DegU]]-P [http://www.ncbi.nlm.nih.gov/sites/entrez/19420703 PubMed]
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| * '''Additional information:''' The operon is not expressed in the lab strain 168 due to lack of expression of [[DegQ]] resulting in inactivity of [[DegS]] and [[DegU]] {{PubMed|21965392}}
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| =Biological materials =
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| * '''Mutant:'''
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| * '''Expression vector:'''
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| * '''lacZ fusion:'''
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| * '''GFP fusion:'''
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| * '''two-hybrid system:'''
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| * '''Antibody:'''
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| =Labs working on this gene/protein=
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| =Your additional remarks=
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| =References=
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| ==Reviews==
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| <pubmed>20735481 </pubmed>
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| ==Original publications==
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| '''Additional publications:''' {{PubMed|21965392}}
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| <pubmed>11751809,19420703, 16233197 20564357 20564574 </pubmed>
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| [[Category:Protein-coding genes]]
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