ccdA

168

membrane-embedded thiol-disulfide oxidoreductase

Locus: BSU_17930

Molecular weight: 25.86 kDa

Isoelectric point: 9.67

Protein length: 235 aa

Gene length: 708 bp

Function: cytochrome c synthesis

Product: thiol-disulfide oxidoreductase

Essential: no

Synonyms: ccdA

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG0785 (Galperin et al., 2021)

Gene

Coordinates: 1,923,234  1,923,941

The protein

Protein family

• DsbD family (single member, according to UniProt)

Structure

• 5VKV (PDB) (from Thermus thermophilus, 38% identity) PubMed
• P45706 (AlphaFold)

Localization

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: ccdA-yneI-yneJ

  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in sigA regulon

Biological materials

Mutant

• BKE17930 (ccdA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCATCATCCCTTCATG,  downstream forward: _UP4_TGACGGTAAATTACTTTCGT
• BKK17930 (ccdA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGTCATCATCCCTTCATG,  downstream forward: _UP4_TGACGGTAAATTACTTTCGT

References

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