RecD2

• Description: 5'-3' DNA helicase replication fork progression
  
  

Gene name	yrrC
Synonyms
Essential	no
Product	5'-3' DNA helicase
Function	replication fork progression
Gene expression levels in SubtiExpress: RecD2
Interactions involving this protein in SubtInteract: RecD2
MW, pI	88 kDa, 5.08
Gene length, protein length	2394 bp, 798 aa
Immediate neighbours	yrrD, yrrB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA replication

The gene

Basic information

• Locus tag: BSU27480

Phenotypes of a mutant

• modest increase in spontaneous mutation rate PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • SsbA-RecD2 PubMed

• Localization:

Database entries

• Structure:

• UniProt: O34481

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: recD2 PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Brian W Walsh, Samantha A Bolz, Sarah R Wessel, Jeremy W Schroeder, James L Keck, Lyle A Simmons
RecD2 helicase limits replication fork stress in Bacillus subtilis.
J Bacteriol: 2014, 196(7);1359-68
[PubMed:24443534] [WorldCat.org] [DOI] (I p)

Audrey Costes, François Lecointe, Stephen McGovern, Sophie Quevillon-Cheruel, Patrice Polard
The C-terminal domain of the bacterial SSB protein acts as a DNA maintenance hub at active chromosome replication forks.
PLoS Genet: 2010, 6(12);e1001238
[PubMed:21170359] [WorldCat.org] [DOI] (I e)