ldt

ldt
168

L,D-transpeptidase involved in cell wall synthesis

Locus
BSU_14040
Molecular weight
17.59 kDa
Isoelectric point
10.25
Protein length
Gene length
Function
cell wall biosynthesis
Product
L,D-transpeptidase
Essential
no
Synonyms
ldt, ykuD

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1388 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,476,518  1,477,012
The protein
Protein family
YkuD family (with YciB and YqjB, according to UniProt)
contains a N-terminal N-acetylglucosamine-polymer-binding LysM domain PubMed
LysM domain (aa 2-45) (according to UniProt)
Structure
2MTZ (PDB) (complex with a peptidoglycan hexamuropeptide) PubMed
Paralogous protein(s)
spore wall (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
Description
Regulation
expressed during sporulation in the mother cell (SigK) PubMed
Regulatory mechanism
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigK: sigma factor, PubMed, in sigK regulon
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ldt

2025-05-09 19:53:41

ghost

82

b45eb98f9bf48c0ce86be9078f99910a86b728e0

135B2E0D94104844F0BA2B2EE17FDDD19CA36C91

Description
Regulation
expressed during sporulation in the mother cell (SigK) PubMed
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ykuEykuC

2025-05-09 19:14:58

ghost

102

900f4f5bf9b6f18854e49d4fcb50b165e30a6ce2

AB2193A8638597380A2AEFF9607482D0824BD9F0

Biological materials
Mutant
MGNA-A766 (ykuD::erm), available at the NBRP B. subtilis, Japan
BKE14040 (ldt::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAGTTTCCTCATCCTCCTTT,  downstream forward: _UP4_TAATGTTTTCTTATTTGTTT
BKK14040 (ldt::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CAGTTTCCTCATCCTCCTTT,  downstream forward: _UP4_TAATGTTTTCTTATTTGTTT
References
Reviews
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Original Publications
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6F256986E591DB82974A7F54EB1CE0C024A6F63B

Page visits: 3610

Time of last update: 2025-05-09 23:33:50

Author of last update: Jstuelk