TlpC

• Description: membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein
  
  

Gene name	tlpC
Synonyms
Essential	no
Product	methyl-accepting chemotaxis protein
Function	control of chemotaxis
Gene expression levels in SubtiExpress: tlpC
MW, pI	61 kDa, 4.929
Gene length, protein length	1719 bp, 573 aa
Immediate neighbours	nucA, hxlB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

motility and chemotaxis, membrane proteins

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

• Locus tag: BSU03440

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane PubMed

Database entries

• Structure:

• UniProt: P39209

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tlpC PubMed

• Expression browser: tlpC PubMed

• Sigma factor: SigD PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:
  • in minimal medium,TlpC is present with 5,400 +/- 1700 molecules per cell PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Vincent J Cannistraro, George D Glekas, Christopher V Rao, George W Ordal
Cellular stoichiometry of the chemotaxis proteins in Bacillus subtilis.
J Bacteriol: 2011, 193(13);3220-7
[PubMed:21515776] [WorldCat.org] [DOI] (I p)

D van Sinderen, R Kiewiet, G Venema
Differential expression of two closely related deoxyribonuclease genes, nucA and nucB, in Bacillus subtilis.
Mol Microbiol: 1995, 15(2);213-23
[PubMed:7746143] [WorldCat.org] [DOI] (P p)

D W Hanlon, M M Rosario, G W Ordal, G Venema, D Van Sinderen
Identification of TlpC, a novel 62 kDa MCP-like protein from Bacillus subtilis.
Microbiology (Reading): 1994, 140 ( Pt 8);1847-54
[PubMed:7921238] [WorldCat.org] [DOI] (P p)