Difference between revisions of "RpsL"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybxF]]'', ''[[rpsG]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ybxF]]'', ''[[rpsG]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01100 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU01100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU01100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU01100 DNA_with_flanks]
 
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Revision as of 09:15, 14 May 2013

Gene name rpsL
Synonyms strA, fun
Essential yes PubMed
Product ribosomal protein S12 (BS12)
Function translation
Gene expression levels in SubtiExpress: rpsL
Interactions involving this protein in SubtInteract: RpsL
MW, pI 15 kDa, 11.721
Gene length, protein length 414 bp, 138 aa
Immediate neighbours ybxF, rpsG
Sequences Protein DNA DNA_with_flanks
Genetic context
RpsL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RpsL expression.png















Categories containing this gene/protein

translation, essential genes, phosphoproteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU01100

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-123 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Alexander K W Elsholz, Kürsad Turgay, Stephan Michalik, Bernd Hessling, Katrin Gronau, Dan Oertel, Ulrike Mäder, Jörg Bernhardt, Dörte Becher, Michael Hecker, Ulf Gerth
Global impact of protein arginine phosphorylation on the physiology of Bacillus subtilis.
Proc Natl Acad Sci U S A: 2012, 109(19);7451-6
[PubMed:22517742] [WorldCat.org] [DOI] (I p)

Matthew A Lauber, William E Running, James P Reilly
B. subtilis ribosomal proteins: structural homology and post-translational modifications.
J Proteome Res: 2009, 8(9);4193-206
[PubMed:19653700] [WorldCat.org] [DOI] (P p)

Kazuhiko Kurosawa, Takeshi Hosaka, Norimasa Tamehiro, Takashi Inaoka, Kozo Ochi
Improvement of alpha-amylase production by modulation of ribosomal component protein S12 in Bacillus subtilis 168.
Appl Environ Microbiol: 2006, 72(1);71-7
[PubMed:16391027] [WorldCat.org] [DOI] (P p)

T Inaoka, K Kasai, K Ochi
Construction of an in vivo nonsense readthrough assay system and functional analysis of ribosomal proteins S12, S4, and S5 in Bacillus subtilis.
J Bacteriol: 2001, 183(17);4958-63
[PubMed:11489846] [WorldCat.org] [DOI] (P p)