Pmi

• Description: mannose-6-phosphate isomerase
  
  

Gene name	pmi
Synonyms	yvyI
Essential	no
Product	mannose-6-phosphate isomerase
Function	mannose utilization
Gene expression levels in SubtiExpress: pmi
MW, pI	35 kDa, 4.982
Gene length, protein length	948 bp, 316 aa
Immediate neighbours	lytD, gerBA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources

The gene

Basic information

• Locus tag: BSU35790

Database entries

• BsubCyc: BSU35790

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-mannose 6-phosphate = D-fructose 6-phosphate (according to Swiss-Prot)

• Protein family: mannose-6-phosphate isomerase type 1 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU35790

• Structure: 1QWR

• UniProt: P39841

• KEGG entry: [3]

• E.C. number: 5.3.1.8

Expression and regulation

• Operon: pmi PubMed

• Expression browser: pmi PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Soo-Jin Yeom, Yeong-Su Kim, Deok-Kun Oh
Development of novel sugar isomerases by optimization of active sites in phosphosugar isomerases for monosaccharides.
Appl Environ Microbiol: 2013, 79(3);982-8
[PubMed:23204422] [WorldCat.org] [DOI] (I p)

P Margot, C Mauël, D Karamata
The gene of the N-acetylglucosaminidase, a Bacillus subtilis 168 cell wall hydrolase not involved in vegetative cell autolysis.
Mol Microbiol: 1994, 12(4);535-45
[PubMed:7934877] [WorldCat.org] [DOI] (P p)