HutH

From SubtiWiki
Revision as of 17:11, 24 May 2009 by Sroppel (talk | contribs)
Jump to: navigation, search
  • Description: histidase

Gene name hutH
Synonyms
Essential no
Product histidase
Function histidine utilization
MW, pI 55 kDa, 5.221
Gene length, protein length 1524 bp, 508 aa
Immediate neighbours hutP, hutU
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
HutH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: L-histidine = urocanate + NH3 (according to Swiss-Prot)
  • Protein family: PAL/histidase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP1114 (spc), available in Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Fisher SH, Magasanik B (1984) 2-Ketoglutarate and the regulation of aconitase and histidase formation Bacillus subtilis. J Bacteriol 158:379-382. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed