DynA

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  • Description: dynamin-like protein, mediates membrane fusion

Gene name dynA
Synonyms ypbR
Essential no
Product dynamin-like protein
Function fusion of membranes
Gene expression levels in SubtiExpress: dynA
Interactions involving this protein in SubtInteract: DynA
MW, pI 137 kDa, 5.724
Gene length, protein length 3579 bp, 1193 aa
Immediate neighbours ypbS, fbpC
Sequences Protein DNA Advanced_DNA
Genetic context
YpbR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DynA expression.png















Categories containing this gene/protein

cell division, cell shape, membrane dynamics, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU22030

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: mediates nucleotide independent membrane fusion in vitro PubMed
  • Protein family: gerABKA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two separate dynamin-like subunits and GTPase domains PubMed
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Marc Bramkamp
Structure and function of bacterial dynamin-like proteins.
Biol Chem: 2012, 393(11);1203-14
[PubMed:23109540] [WorldCat.org] [DOI] (I p)

Sandra L Schmid, Vadim A Frolov
Dynamin: functional design of a membrane fission catalyst.
Annu Rev Cell Dev Biol: 2011, 27;79-105
[PubMed:21599493] [WorldCat.org] [DOI] (I p)

Harry H Low, Jan Löwe
Dynamin architecture--from monomer to polymer.
Curr Opin Struct Biol: 2010, 20(6);791-8
[PubMed:20970992] [WorldCat.org] [DOI] (I p)

Gerrit J K Praefcke, Harvey T McMahon
The dynamin superfamily: universal membrane tubulation and fission molecules?
Nat Rev Mol Cell Biol: 2004, 5(2);133-47
[PubMed:15040446] [WorldCat.org] [DOI] (P p)

Original publications