CsbC

• Description: general stress protein, similar to pentose transporter
  
  

Gene name	csbC
Synonyms	yxcC
Essential	no
Product	putative pentose transporter
Function	unknown
Gene expression levels in SubtiExpress: csbC
MW, pI	49 kDa, 9.943
Gene length, protein length	1383 bp, 461 aa
Immediate neighbours	yxcD, htpG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, general stress proteins (controlled by SigB), membrane proteins

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

• Locus tag: BSU39810

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • CsbC is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P46333

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: csbC PubMed

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Elodie Marchadier, Rut Carballido-López, Sophie Brinster, Céline Fabret, Peggy Mervelet, Philippe Bessières, Marie-Françoise Noirot-Gros, Vincent Fromion, Philippe Noirot
An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach.
Proteomics: 2011, 11(15);2981-91
[PubMed:21630458] [WorldCat.org] [DOI] (I p)

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

Samina Akbar, Soon Youl Lee, Sharon A Boylan, Chester W Price
Two genes from Bacillus subtilis under the sole control of the general stress transcription factor sigmaB.
Microbiology (Reading): 1999, 145 ( Pt 5);1069-1078
[PubMed:10376822] [WorldCat.org] [DOI] (P p)