BdhA

• Description: acetoine/ butanediol dehydrogenase
  
  

Gene name	bdhA
Synonyms	ydjL
Essential	no
Product	acetoine/ butanediol dehydrogenase
Function	overflow metabolism, fermentation
Gene expression levels in SubtiExpress: bdhA
MW, pI	37 kDa, 4.805
Gene length, protein length	1038 bp, 346 aa
Immediate neighbours	iolT, ydjM
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

carbon core metabolism, phosphoproteins, most abundant proteins

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU06240

Database entries

• BsubCyc: BSU06240

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: formation of butanediol from acetoin PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:
  • phosphorylated on Arg-13 PubMed

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU06240

• Structure:

• UniProt: O34788

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: bdhA (according to DBTBS)

• Expression browser: bdhA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:
  • The mRNA has a long (268 nt) untranslated leader region PubMed
  • belongs to the 100 most abundant proteins PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 3845 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 7816 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: