ClpQ

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  • Description: two-component ATP-dependent protease

Gene name clpQ
Synonyms hslV, codW
Essential no
Product two-component ATP-dependent protease
Function protein degradation
Gene expression levels in SubtiExpress: clpQ
Interactions involving this protein in SubtInteract: ClpQ
MW, pI 19 kDa, 6.105
Gene length, protein length 543 bp, 181 aa
Immediate neighbours codV, clpY
Sequences Protein DNA DNA_with_flanks
Genetic context
ClpQ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ClpQ expression.png















Categories containing this gene/protein

proteolysis, membrane proteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU16150

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: HslV subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cytoplasm, forms small foci, usually positioned near the cell membrane, formation of foci depends on the presence of the cognate ATPase ClpY PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Additional reviews: PubMed

Original publications