lrpB

168

transcriptional regulator (Lrp family) involved in repression of glyA transcription and KinB-dependent sporulation

Locus: BSU_05060

Molecular weight: 17.18 kDa

Isoelectric point: 6.68

Protein length: 149 aa

Gene length: 450 bp

Function: repression of glyA transcription and KinB-dependent sporulation

Product: transcription regulator (Lrp family)

Essential: no

Synonyms: lrpB, yddP

Genomic Context

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List of homologs in different organisms, belongs to COG1522 (Galperin et al., 2021)

Gene

Coordinates: 552,052  552,501

The protein

Protein family

• (Lrp family)

Domains

• HTH asnC-type domain (aa 3-64) (according to UniProt)

Structure

• 2CFX (PDB) (LrpC, 31% identity) PubMed
• P96653 (AlphaFold)

Biological materials

Mutant

• MGNA-C110 (yczA::erm), available at the NBRP B. subtilis, Japan
• BKE05060 (lrpB::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGTAACTCCTTTCACAG,  downstream forward: _UP4_TAATGCGCTTGTTATTATAA
• BKK05060 (lrpB::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAGTAACTCCTTTCACAG,  downstream forward: _UP4_TAATGCGCTTGTTATTATAA

References

Research papers

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