PucC

From SubtiWiki
Revision as of 13:15, 18 June 2009 by CLammers (talk | contribs)
Jump to: navigation, search
  • Description: xanthine dehydrogenase

Gene name pucC
Synonyms yurD
Essential no
Product xanthine dehydrogenase
Function purine utilization
Metabolic function and regulation of this protein in SubtiPathways:
Purine catabolism, Nucleotides (regulation)
MW, pI 29 kDa, 8.576
Gene length, protein length 831 bp, 277 aa
Immediate neighbours pucD, pucB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PucC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU32490

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Xanthine + NAD+ + H2O = urate + NADH (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed in the absence of purine nucleotides (inducer: allantoin) (PucR) PubMed
  • Regulatory mechanism:
    • [PucR]]: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References