YhfR

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  • Description: involved in isopentenol (isoprenoid) biosynthesis

Gene name yhfR
Synonyms
Essential no
Product unknown
Function isoprenoid biosynthesis
MW, pI 21 kDa, 5.164
Gene length, protein length 579 bp, 193 aa
Immediate neighbours yhfQ, yhfS
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhfR context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU10340

Phenotypes of a mutant

no detectable phenotype PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: unknown PubMed
  • Protein family: GpmB subfamily (according to Swiss-Prot) similar to 2,3-diphosphoglycerate-dependent phosphoglycerate mutases PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information: weakly expressed PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sydnor T Withers, Shayin S Gottlieb, Bonny Lieu, Jack D Newman, Jay D Keasling
Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity.
Appl Environ Microbiol: 2007, 73(19);6277-83
[PubMed:17693564] [WorldCat.org] [DOI] (P p)

C L Pearson, C A Loshon, L B Pedersen, B Setlow, P Setlow
Analysis of the function of a putative 2,3-diphosphoglyceric acid-dependent phosphoglycerate mutase from Bacillus subtilis.
J Bacteriol: 2000, 182(14);4121-3
[PubMed:10869096] [WorldCat.org] [DOI] (P p)