SigD

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Gene name sigD
Synonyms flaB
Essential no
Product RNA polymerase sigma factor SigD
Function regulation of flagella, motility, chemotaxis and autolysis
MW, pI 29 kDa, 5.167
Gene length, protein length 762 bp, 254 aa
Immediate neighbours cheD, swrB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SigD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU16470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: sigma-70 factor family (according to Swiss-Prot)
  • Paralogous protein(s):

Genes/ operons controlled by SigD

dltA-dltB-dltC-dltD-dltE, cheV, degR, epr, hag, lytA-lytB-lytC, lytD, lytF, tlpA-mcpA, mcpB, mcpC, motA-motB, nfrA-ywcH

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed