CtaA

• Description: heme A synthase
  
  

Gene name	ctaA
Synonyms
Essential	no
Product	heme A synthase
Function	heme biosynthesis
MW, pI	33 kDa, 9.644
Gene length, protein length	918 bp, 306 aa
Immediate neighbours	pycA, ctaB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU14870

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: COX15/ctaA family, Type 1 subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P12946

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tatsushi Mogi
Probing structure of heme A synthase from Bacillus subtilis by site-directed mutagenesis.
J Biochem: 2009, 145(5);625-33
[PubMed:19174544] [WorldCat.org] [DOI] (I p)

X Zhang, F M Hulett
ResD signal transduction regulator of aerobic respiration in Bacillus subtilis: ctaA promoter regulation.
Mol Microbiol: 2000, 37(5);1208-19
[PubMed:10972837] [WorldCat.org] [DOI] (P p)

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed