RpoA

• Description: RNA polymerase alpha subunit
  
  

Gene name	rpoA
Synonyms
Essential	yes PubMed
Product	RNA polymerase alpha subunit
Function	transcription
MW, pI	34 kDa, 4.593
Gene length, protein length	942 bp, 314 aa
Immediate neighbours	rpsK, rplQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1) (according to Swiss-Prot)

• Protein family: RNA polymerase alpha chain family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: RpoA-Spx, RpoA-RpoB-RpoC

• Localization:

Database entries

• Structure: 1Z3E (C-terminal domain, complex with Spx)

• Swiss prot entry: P20429

• KEGG entry: BSU01430

• E.C. number: 2.7.7.6

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed