OxdC

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  • Description: oxalate decarboxylase

Gene name oxdC
Synonyms yvrK
Essential no
Product oxalate decarboxylase
Function unknown
MW, pI 43 kDa, 5.101
Gene length, protein length 1155 bp, 385 aa
Immediate neighbours yvrJ, yvrL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
OxdC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Oxalate = formate + CO2 (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s): OxdD

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): requires Mn(II) for activity PubMed
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

Additional information

Expression and regulation

  • Regulation: induced by acidic growth conditions PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References

Ellen W Moomaw, Alexander Angerhofer, Patricia Moussatche, Andrew Ozarowski, Inés García-Rubio, Nigel G J Richards
Metal dependence of oxalate decarboxylase activity.
Biochemistry: 2009, 48(26);6116-25
[PubMed:19473032] [WorldCat.org] [DOI] (I p)

Shawn R MacLellan, John D Helmann, Haike Antelmann
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
J Bacteriol: 2009, 191(3);931-9
[PubMed:19047353] [WorldCat.org] [DOI] (I p)


  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed