UxuA

• Description: D-mannonate hydrolyase
  
  

Gene name	uxuA
Synonyms	yjmE
Essential	no
Product	D-mannonate hydrolyase
Function	hexuronate utilization
MW, pI	40 kDa, 4.92
Gene length, protein length	1077 bp, 359 aa
Immediate neighbours	yjmD, yjmF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H₂O (according to Swiss-Prot)

• Protein family: mannonate dehydratase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: O34346

• KEGG entry: BSU12340

• E.C. number: 4.2.1.8

Expression and regulation

• Operon:

• Sigma factor:

• Regulation: repressed by glucose (CcpA)

• Regulatory mechanism: CcpA: transcription repression

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed