SsbA

• Description: single-strand DNA-binding protein
  
  

Gene name	ssb
Synonyms
Essential	yes PubMed
Product	single-strand DNA-binding protein
Function	DNA replication, recombination, repair
MW, pI	18 kDa, 4.822
Gene length, protein length	516 bp, 172 aa
Immediate neighbours	rpsR, rpsF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): YwpH

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on Tyr-82 by PtkA, dephosphorylated by PtpZ PubMed

• Cofactor(s):

• Effectors of protein activity: Phosphorylation of Ssb increases binding to single-stranded DNA in vitro almost 200-fold PubMed

• Interactions:

• Localization: Nucleoid (Mid-cell) PubMed

Database entries

• Structure:

• Swiss prot entry: P37455

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Meile et al. (2006) Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory Proteomics 6: 2135-2146. PubMed
2. Mijakovic I, Petranovic D, Macek B, Cepo T, Mann M, Davies J, Jensen PR, Vujaklija D: Bacterial single-stranded DNA-binding proteins are phosphorylated on tyrosine. Nucl Acids Res 2006, 34:1588-1596. PubMed
3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed