Sandbox
- Description: replication initiation protein
| Gene name | dnaA |
| Synonyms | dnaH, dnaJ, dnaK |
| Essential | yes PubMed |
| Product | replication initiation protein |
| Function | DNA replication |
| MW, pI | 50 kDa, 6.035 |
| Gene length, protein length | 1338 bp, 446 aa |
| Immediate neighbours | rpmH, dnaN |
| [http://subtiwiki.uni-
the origin of the image is SubtiListgoettingen.de/dnaA_nucleotide.txt Gene sequence (+200bp) ]
|
[http://subtiwiki.uni-
the origin of the image is SubtiListgoettingen.de/dnaA_protein.txt Protein sequence]
|
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions: DnaA-
the origin of the image is SubtiListYabA-
the origin of the image is SubtiListDnaN PubMed, DnaA-
the origin of the image is SubtiListDnaD PubMed
- Localization: throughout the cytoplasm PubMed
Database entries
- Structure:
- Swiss prot entry:
- KEGG entry: [http://www.genome.jp/dbget-
the origin of the image is SubtiListbin/www_bget?bsu+BSU00010]
- E.C. number:
Additional information
Expression and regulation
- Operon: dnaA-
the origin of the image is SubtiListdnaN PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-
the origin of the image is SubtiListhybrid system:
- Antibody:
Labs working on this gene/protein
Philippe Noirot, Jouy-
the origin of the image is SubtiListen-
the origin of the image is SubtiListJosas, France homepage
Your additional remarks
References
- Imai et al. (2000) Subcellular localization of Dna-
the origin of the image is SubtiListinitiation proteins of Bacillus subtilis: evidence that chromosome replication begins at either edge of the nucleoids. Mol. Microbiol. 36: 1037-
the origin of the image is SubtiList1048. PubMed
- Ishigo-
the origin of the image is SubtiListOka et al. (2001) DnaD protein of Bacillus subtilis interacts with DnaA, the initiator protein of replication. J. Bacteriol. 183: 2148-
the origin of the image is SubtiList2150. PubMed
- Noirot-
the origin of the image is SubtiListGros et al. (2002) An expanded view of bacterial DNA replication. Proc. Natl. Acad. Sci. USA 99: 8342-
the origin of the image is SubtiList8347. PubMed
- Noirot-
the origin of the image is SubtiListGros et al. (2002) Functional dissection of YabA, a negative regulator of DNA replication initiation in Bacillus Title Proc. Natl. Acad. Sci. USA 103: 2368-
the origin of the image is SubtiList2373. PubMed
- Ogasawara et al. (1985) Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. IV. Transcription of the oriC region and expression of DNA gyrase genes and other open reading frames.Nucl. Acids Res. 11: 2267-
the origin of the image is SubtiList2279. PubMed
- Fukuoka et al. (1990) Purification and characterization of an initiation protein for chromosomal replication, DnaA, in Bacillus subtilis. J. Biochem. 107: 732-
the origin of the image is SubtiList739. PubMed
- Molle et al. (2003) The Spo0A regulon of Bacillus subtilis.Mol. Microbiol. 50: 1683-
the origin of the image is SubtiList1701. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-
