Akos T Kovacs

Photo by Wout Overkamp[1].

Akos T Kovacs

• Current position: Professor of Bacterial Physiology and Genetics at the Technical University of Denmark (2017-)
• Habilitation (2016), PhD (2003)
• Contact: atkovacs@dtu.dk send mail

Research Interests

• bacterial biofilm development
• phenotypic heterogeneity
• Bacillus subtilis
• Bacillus cereus
• interaction of Bacilli and fungi
• evolution in biofilms
• microbial cooperation and competition

Publications

Pubmed

Recent publications (2014-2021)

Sofia Arnaouteli, Natalie C Bamford, Nicola R Stanley-Wall, Ákos T Kovács
Bacillus subtilis biofilm formation and social interactions.
Nat Rev Microbiol: 2021, 19(9);600-614
[PubMed:33824496] [WorldCat.org] [DOI] (I p)

Kat Steinke, Omkar S Mohite, Tilmann Weber, Ákos T Kovács
Phylogenetic Distribution of Secondary Metabolites in the Bacillus subtilis Species Complex.
mSystems: 2021, 6(2);
[PubMed:33688015] [WorldCat.org] [DOI] (P e)

Heiko T Kiesewalter, Carlos N Lozano-Andrade, Mario Wibowo, Mikael L Strube, Gergely Maróti, Dan Snyder, Tue Sparholt Jørgensen, Thomas O Larsen, Vaughn S Cooper, Tilmann Weber, Ákos T Kovács
Genomic and Chemical Diversity of Bacillus subtilis Secondary Metabolites against Plant Pathogenic Fungi.
mSystems: 2021, 6(1);
[PubMed:33622852] [WorldCat.org] [DOI] (P e)

Zheng Eelderink-Chen, Jasper Bosman, Francesca Sartor, Antony N Dodd, Ákos T Kovács, Martha Merrow
A circadian clock in a nonphotosynthetic prokaryote.
Sci Adv: 2021, 7(2);
[PubMed:33523996] [WorldCat.org] [DOI] (I e)

Maude Thérien, Heiko T Kiesewalter, Emile Auria, Vincent Charron-Lamoureux, Mario Wibowo, Gergely Maróti, Ákos T Kovács, Pascale B Beauregard
##Title##
Biofilm: 2020, 2;100021
[PubMed:33447807] [WorldCat.org] [DOI] (I e)

Raimo Hartmann, Hannah Jeckel, Eric Jelli, Praveen K Singh, Sanika Vaidya, Miriam Bayer, Daniel K H Rode, Lucia Vidakovic, Francisco Díaz-Pascual, Jiunn C N Fong, Anna Dragoš, Olga Lamprecht, Janne G Thöming, Niklas Netter, Susanne Häussler, Carey D Nadell, Victor Sourjik, Ákos T Kovács, Fitnat H Yildiz, Knut Drescher
Quantitative image analysis of microbial communities with BiofilmQ.
Nat Microbiol: 2021, 6(2);151-156
[PubMed:33398098] [WorldCat.org] [DOI] (I p)

Anna Dragoš, B Priyadarshini, Zahraa Hasan, Mikael Lenz Strube, Paul J Kempen, Gergely Maróti, Charlotte Kaspar, Baundauna Bose, Briana M Burton, Ilka B Bischofs, Ákos T Kovács
Pervasive prophage recombination occurs during evolution of spore-forming Bacilli.
ISME J: 2021, 15(5);1344-1358
[PubMed:33343000] [WorldCat.org] [DOI] (I p)

Heiko T Kiesewalter, Carlos N Lozano-Andrade, Mikael L Strube, Ákos T Kovács
##Title##
Beilstein J Org Chem: 2020, 16;2983-2998
[PubMed:33335606] [WorldCat.org] [DOI] (P e)

Ravindra Garde, Jan Ewald, Ákos T Kovács, Stefan Schuster
Modelling population dynamics in a unicellular social organism community using a minimal model and evolutionary game theory.
Open Biol: 2020, 10(11);200206
[PubMed:33142084] [WorldCat.org] [DOI] (I p)

Ákos T Kovács
A fungal scent from the cheese.
Environ Microbiol: 2020, 22(11);4524-4526
[PubMed:33000496] [WorldCat.org] [DOI] (I p)

Christopher Blake, Mathilde Nordgaard Christensen, Ákos T Kovács
##Title##
Mol Plant Microbe Interact: 2021, 34(1);15-25
[PubMed:32986513] [WorldCat.org] [DOI] (P p)

Simon B Otto, Marivic Martin, Daniel Schäfer, Raimo Hartmann, Knut Drescher, Susanne Brix, Anna Dragoš, Ákos T Kovács
Privatization of Biofilm Matrix in Structurally Heterogeneous Biofilms.
mSystems: 2020, 5(4);
[PubMed:32753507] [WorldCat.org] [DOI] (P e)

Marivic Martin, Anna Dragoš, Simon B Otto, Daniel Schäfer, Susanne Brix, Gergely Maróti, Ákos T Kovács
Cheaters shape the evolution of phenotypic heterogeneity in Bacillus subtilis biofilms.
ISME J: 2020, 14(9);2302-2312
[PubMed:32483306] [WorldCat.org] [DOI] (I p)

Ravindra Garde, Bashar Ibrahim, Ákos T Kovács, Stefan Schuster
##Title##
R Soc Open Sci: 2020, 7(2);190810
[PubMed:32257302] [WorldCat.org] [DOI] (P e)

Carolina Falcón García, Martin Kretschmer, Carlos N Lozano-Andrade, Markus Schönleitner, Anna Dragoŝ, Ákos T Kovács, Oliver Lieleg
##Title##
NPJ Biofilms Microbiomes: 2020, 6;1
[PubMed:31908831] [WorldCat.org] [DOI] (I e)

Bodil Kjeldgaard, Stevanus A Listian, Valliyammai Ramaswamhi, Anne Richter, Heiko T Kiesewalter, Ákos T Kovács
##Title##
Biofilm: 2019, 1;100007
[PubMed:33447794] [WorldCat.org] [DOI] (I e)

Sagarika Devi, Heiko T Kiesewalter, Renátó Kovács, Jens Christian Frisvad, Tilmann Weber, Thomas Ostenfeld Larsen, Ákos T Kovács, Ling Ding
##Title##
Synth Syst Biotechnol: 2019, 4(3);142-149
[PubMed:31508511] [WorldCat.org] [DOI] (I e)

Tom Coenye, Birthe Veno Kjellerup, Ákos T Kovács, Darla Goeres
Biofilm: Introducing a new journal for the broad biofilm field.
Biofilm: 2019, 1;100003
[PubMed:33447790] [WorldCat.org] [DOI] (I e)

I López-Goñi, J Giner-Lamia, A Álvarez-Ordoñez, Alfonso Benitez-Páez, D Claessen, M Cortesao, M de Toro, D García-Ruano, E T Granato, Á T Kovács, J L Romalde, T G Sana, M Sánchez-Angulo, F J Sangari, W K Smits, T Sturm, J L Thomassin, K N G Valdehuesa, M Zapotoczna
#EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide.
FEMS Microbiol Lett: 2019, 366(11);
[PubMed:31253991] [WorldCat.org] [DOI] (I p)

Francesca Sartor, Zheng Eelderink-Chen, Ben Aronson, Jasper Bosman, Lauren E Hibbert, Antony N Dodd, Ákos T Kovács, Martha Merrow
Are There Circadian Clocks in Non-Photosynthetic Bacteria?
Biology (Basel): 2019, 8(2);
[PubMed:31121908] [WorldCat.org] [DOI] (P e)

Ákos T Kovács
Bacillus subtilis.
Trends Microbiol: 2019, 27(8);724-725
[PubMed:31000489] [WorldCat.org] [DOI] (I p)

Katharina Wagner, Katrin Krause, Ramses Gallegos-Monterrosa, Dominik Sammer, Ákos T Kovács, Erika Kothe
##Title##
Front Microbiol: 2019, 10;307
[PubMed:30842767] [WorldCat.org] [DOI] (P e)

Ákos T Kovács, Anna Dragoš
Evolved Biofilm: Review on the Experimental Evolution Studies of Bacillus subtilis Pellicles.
J Mol Biol: 2019, 431(23);4749-4759
[PubMed:30769118] [WorldCat.org] [DOI] (I p)

Anne Richter, Theresa Hölscher, Patrick Pausch, Tim Sehrt, Franziska Brockhaus, Gert Bange, Ákos T Kovács
Hampered motility promotes the evolution of wrinkly phenotype in Bacillus subtilis.
BMC Evol Biol: 2018, 18(1);155
[PubMed:30326845] [WorldCat.org] [DOI] (I e)

Anna Dragoš, Marivic Martin, Carolina Falcón García, Lara Kricks, Patrick Pausch, Thomas Heimerl, Balázs Bálint, Gergely Maróti, Gert Bange, Daniel López, Oliver Lieleg, Ákos T Kovács
Collapse of genetic division of labour and evolution of autonomy in pellicle biofilms.
Nat Microbiol: 2018, 3(12);1451-1460
[PubMed:30297741] [WorldCat.org] [DOI] (I p)

Anna Dragoš, Heiko Kiesewalter, Marivic Martin, Chih-Yu Hsu, Raimo Hartmann, Tobias Wechsler, Carsten Eriksen, Susanne Brix, Knut Drescher, Nicola Stanley-Wall, Rolf Kümmerli, Ákos T Kovács
Division of Labor during Biofilm Matrix Production.
Curr Biol: 2018, 28(12);1903-1913.e5
[PubMed:29887307] [WorldCat.org] [DOI] (I p)

Diana S Raie, Eisha Mhatre, Doaa S El-Desouki, Ahmed Labena, Gamal El-Ghannam, Laila A Farahat, Tareq Youssef, Wolfgang Fritzsche, Ákos T Kovács
Effect of Novel Quercetin Titanium Dioxide-Decorated Multi-Walled Carbon Nanotubes Nanocomposite on Bacillus subtilis Biofilm Development.
Materials (Basel): 2018, 11(1);
[PubMed:29346268] [WorldCat.org] [DOI] (P e)

Marielle H van den Esker, Ákos T Kovács, Oscar P Kuipers
From Cell Death to Metabolism: Holin-Antiholin Homologues with New Functions.
mBio: 2017, 8(6);
[PubMed:29208748] [WorldCat.org] [DOI] (I e)

James P Tauber, Ramses Gallegos-Monterrosa, Ákos T Kovács, Ekaterina Shelest, Dirk Hoffmeister
Dissimilar pigment regulation in Serpula lacrymans and Paxillus involutus during inter-kingdom interactions.
Microbiology (Reading): 2018, 164(1);65-77
[PubMed:29205129] [WorldCat.org] [DOI] (I p)

Anna Dragoš, Nivedha Lakshmanan, Marivic Martin, Balázs Horváth, Gergely Maróti, Carolina Falcón García, Oliver Lieleg, Ákos T Kovács
Evolution of exploitative interactions during diversification in Bacillus subtilis biofilms.
FEMS Microbiol Ecol: 2017, 93(12);
[PubMed:29126191] [WorldCat.org] [DOI] (I p)

Theresa Hölscher, Tina Schiklang, Anna Dragoš, Anne-Kathrin Dietel, Christian Kost, Ákos T Kovács
Impaired competence in flagellar mutants of Bacillus subtilis is connected to the regulatory network governed by DegU.
Environ Microbiol Rep: 2018, 10(1);23-32
[PubMed:29124898] [WorldCat.org] [DOI] (I p)

Ákos T Kovács, Roberto Grau, Eric J G Pollitt
##Title##
Proc Natl Acad Sci U S A: 2017, 114(42);E8802
[PubMed:29073022] [WorldCat.org] [DOI] (I p)

Anna Dragoš, Ákos T Kovács, Dennis Claessen
The Role of Functional Amyloids in Multicellular Growth and Development of Gram-Positive Bacteria.
Biomolecules: 2017, 7(3);
[PubMed:28783117] [WorldCat.org] [DOI] (I e)

Ramses Gallegos-Monterrosa, Stefanie Kankel, Sebastian Götze, Robert Barnett, Pierre Stallforth, Ákos T Kovács
Lysinibacillus fusiformis M5 Induces Increased Complexity in Bacillus subtilis 168 Colony Biofilms via Hypoxanthine.
J Bacteriol: 2017, 199(22);
[PubMed:28583948] [WorldCat.org] [DOI] (I e)

Marivic Martin, Anna Dragoš, Theresa Hölscher, Gergely Maróti, Balázs Bálint, Martin Westermann, Ákos T Kovács
De novo evolved interference competition promotes the spread of biofilm defectors.
Nat Commun: 2017, 8;15127
[PubMed:28462927] [WorldCat.org] [DOI] (I e)

Theresa Hölscher, Ákos T Kovács
Sliding on the surface: bacterial spreading without an active motor.
Environ Microbiol: 2017, 19(7);2537-2545
[PubMed:28370801] [WorldCat.org] [DOI] (I p)

Eisha Mhatre, Anandaroopan Sundaram, Theresa Hölscher, Mike Mühlstädt, Jörg Bossert, Ákos T Kovács
Presence of Calcium Lowers the Expansion of Bacillus subtilis Colony Biofilms.
Microorganisms: 2017, 5(1);
[PubMed:28212310] [WorldCat.org] [DOI] (P e)

Anna Dragoš, Ákos T Kovács
The Peculiar Functions of the Bacterial Extracellular Matrix.
Trends Microbiol: 2017, 25(4);257-266
[PubMed:28089324] [WorldCat.org] [DOI] (I p)

Theresa Hölscher, Anna Dragoš, Ramses Gallegos-Monterrosa, Marivic Martin, Eisha Mhatre, Anne Richter, Ákos T Kovács
Monitoring Spatial Segregation in Surface Colonizing Microbial Populations.
J Vis Exp: 2016, (116);
[PubMed:27842347] [WorldCat.org] [DOI] (I e)

Ramses Gallegos-Monterrosa, Gergely Maróti, Balázs Bálint, Ákos T Kovács
Draft Genome Sequence of the Soil Isolate Lysinibacillus fusiformis M5, a Potential Hypoxanthine Producer.
Genome Announc: 2016, 4(6);
[PubMed:27834716] [WorldCat.org] [DOI] (P e)

Diana S Raie, Eisha Mhatre, Matthias Thiele, A Labena, Gamal El-Ghannam, Laila A Farahat, Tareq Youssef, Wolfgang Fritzsche, Ákos T Kovács
Application of quercetin and its bio-inspired nanoparticles as anti-adhesive agents against Bacillus subtilis attachment to surface.
Mater Sci Eng C Mater Biol Appl: 2017, 70(Pt 1);753-762
[PubMed:27770951] [WorldCat.org] [DOI] (I p)

Judith Krawinkel, Maria Leilani Torres-Mapa, Eisha Mhatre, Ákos T Kovács, Alexander Heisterkamp
Structural damage of Bacillus subtilis biofilms using pulsed laser interaction with gold thin films.
J Biophotonics: 2017, 10(8);1043-1052
[PubMed:27714933] [WorldCat.org] [DOI] (I p)

Ivana Seccareccia, Ákos T Kovács, Ramses Gallegos-Monterrosa, Markus Nett
Unraveling the predator-prey relationship of Cupriavidus necator and Bacillus subtilis.
Microbiol Res: 2016, 192;231-238
[PubMed:27664741] [WorldCat.org] [DOI] (I p)

Ramses Gallegos-Monterrosa, Eisha Mhatre, Ákos T Kovács
Specific Bacillus subtilis 168 variants form biofilms on nutrient-rich medium.
Microbiology (Reading): 2016, 162(11);1922-1932
[PubMed:27655338] [WorldCat.org] [DOI] (I p)

Marielle H van den Esker, Ákos T Kovács, Oscar P Kuipers
YsbA and LytST are essential for pyruvate utilization in Bacillus subtilis.
Environ Microbiol: 2017, 19(1);83-94
[PubMed:27422364] [WorldCat.org] [DOI] (I p)

Eisha Mhatre, Agnieszka Troszok, Ramses Gallegos-Monterrosa, Stefanie Lindstädt, Theresa Hölscher, Oscar P Kuipers, Ákos T Kovács
The impact of manganese on biofilm development of Bacillus subtilis.
Microbiology (Reading): 2016, 162(8);1468-1478
[PubMed:27267987] [WorldCat.org] [DOI] (I p)

Ákos T Kovács
The global regulator CodY is required for the fitness of Bacillus cereus in various laboratory media and certain beverages.
FEMS Microbiol Lett: 2016, 363(13);
[PubMed:27190142] [WorldCat.org] [DOI] (I p)

Marivic Martin, Theresa Hölscher, Anna Dragoš, Vaughn S Cooper, Ákos T Kovács
Laboratory Evolution of Microbial Interactions in Bacterial Biofilms.
J Bacteriol: 2016, 198(19);2564-71
[PubMed:27044625] [WorldCat.org] [DOI] (I e)

Ákos T Kovács
Bacterial differentiation via gradual activation of global regulators.
Curr Genet: 2016, 62(1);125-8
[PubMed:26458398] [WorldCat.org] [DOI] (I p)

Roberto R Grau, Paula de Oña, Maritta Kunert, Cecilia Leñini, Ramses Gallegos-Monterrosa, Eisha Mhatre, Darío Vileta, Verónica Donato, Theresa Hölscher, Wilhelm Boland, Oscar P Kuipers, Ákos T Kovács
A Duo of Potassium-Responsive Histidine Kinases Govern the Multicellular Destiny of Bacillus subtilis.
mBio: 2015, 6(4);e00581
[PubMed:26152584] [WorldCat.org] [DOI] (I e)

Theresa Hölscher, Benjamin Bartels, Yu-Cheng Lin, Ramses Gallegos-Monterrosa, Alexa Price-Whelan, Roberto Kolter, Lars E P Dietrich, Ákos T Kovács
Motility, Chemotaxis and Aerotaxis Contribute to Competitiveness during Bacterial Pellicle Biofilm Development.
J Mol Biol: 2015, 427(23);3695-3708
[PubMed:26122431] [WorldCat.org] [DOI] (I p)

Johannes Schneider, Teresa Klein, Benjamin Mielich-Süss, Gudrun Koch, Christian Franke, Oscar P Kuipers, Ákos T Kovács, Markus Sauer, Daniel Lopez
Spatio-temporal remodeling of functional membrane microdomains organizes the signaling networks of a bacterium.
PLoS Genet: 2015, 11(4);e1005140
[PubMed:25909364] [WorldCat.org] [DOI] (I e)

Ruud G J Detert Oude Weme, Ákos T Kovács, Sander J G de Jong, Jan-Willem Veening, Jeroen Siebring, Oscar P Kuipers
Single cell FRET analysis for the identification of optimal FRET-pairs in Bacillus subtilis using a prototype MEM-FLIM system.
PLoS One: 2015, 10(4);e0123239
[PubMed:25886351] [WorldCat.org] [DOI] (I e)

Akos T Kovács
Impact of spatial distribution on the development of mutualism in microbes.
Front Microbiol: 2014, 5;649
[PubMed:25505463] [WorldCat.org] [DOI] (P e)

Akos T Kovács, Erika Kothe
Special issue: Biofilms.
J Basic Microbiol: 2014, 54(7);615
[PubMed:25041820] [WorldCat.org] [DOI] (I p)

Isabelle Benoit, Marielle H van den Esker, Aleksandrina Patyshakuliyeva, Derek J Mattern, Felix Blei, Miaomiao Zhou, Jan Dijksterhuis, Axel A Brakhage, Oscar P Kuipers, Ronald P de Vries, Ákos T Kovács
Bacillus subtilis attachment to Aspergillus niger hyphae results in mutually altered metabolism.
Environ Microbiol: 2015, 17(6);2099-113
[PubMed:25040940] [WorldCat.org] [DOI] (I p)

Eisha Mhatre, Ramses Gallegos Monterrosa, Akos T Kovács
From environmental signals to regulators: modulation of biofilm development in Gram-positive bacteria.
J Basic Microbiol: 2014, 54(7);616-32
[PubMed:24771632] [WorldCat.org] [DOI] (I p)

Jordi van Gestel, Franz J Weissing, Oscar P Kuipers, Akos T Kovács
Density of founder cells affects spatial pattern formation and cooperation in Bacillus subtilis biofilms.
ISME J: 2014, 8(10);2069-79
[PubMed:24694715] [WorldCat.org] [DOI] (I p)

Öykü İrigül-Sönmez, Türkan E Köroğlu, Büşra Öztürk, Ákos T Kovács, Oscar P Kuipers, Ayten Yazgan-Karataş
In Bacillus subtilis LutR is part of the global complex regulatory network governing the adaptation to the transition from exponential growth to stationary phase.
Microbiology (Reading): 2014, 160(Pt 2);243-260
[PubMed:24196425] [WorldCat.org] [DOI] (I p)

Christine Diethmaier, Joseph A Newman, Akos T Kovács, Volkhard Kaever, Christina Herzberg, Cecilia Rodrigues, Mirjam Boonstra, Oscar P Kuipers, Richard J Lewis, Jörg Stülke
The YmdB phosphodiesterase is a global regulator of late adaptive responses in Bacillus subtilis.
J Bacteriol: 2014, 196(2);265-75
[PubMed:24163345] [WorldCat.org] [DOI] (I p)

Pilar Eliana Puentes-Téllez, Ákos T Kovács, Oscar P Kuipers, Jan Dirk van Elsas
Comparative genomics and transcriptomics analysis of experimentally evolved Escherichia coli MC1000 in complex environments.
Environ Microbiol: 2014, 16(3);856-70
[PubMed:24033913] [WorldCat.org] [DOI] (I p)

Jeroen Siebring, Matthijs J H Elema, Fátima Drubi Vega, Akos T Kovács, Patsy Haccou, Oscar P Kuipers
Repeated triggering of sporulation in Bacillus subtilis selects against a protein that affects the timing of cell division.
ISME J: 2014, 8(1);77-87
[PubMed:23924781] [WorldCat.org] [DOI] (I p)

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