Stusti 2018

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Die Sprache der RNA: Von RNA-Schaltern zu CRISPR/ Cas

Riboswitches


Riboregulation and virulence, targeting by antibiotics


RNA-based second messengers


Ribozymes

Yigong Shi
Mechanistic insights into precursor messenger RNA splicing by the spliceosome.
Nat Rev Mol Cell Biol: 2017, 18(11);655-670
[PubMed:28951565] [WorldCat.org] [DOI] (I p)

Olga Novikova, Marlene Belfort
Mobile Group II Introns as Ancestral Eukaryotic Elements.
Trends Genet: 2017, 33(11);773-783
[PubMed:28818345] [WorldCat.org] [DOI] (I p)

Yigong Shi
The Spliceosome: A Protein-Directed Metalloribozyme.
J Mol Biol: 2017, 429(17);2640-2653
[PubMed:28733144] [WorldCat.org] [DOI] (I p)

Nayef Jarrous
Roles of RNase P and Its Subunits.
Trends Genet: 2017, 33(9);594-603
[PubMed:28697848] [WorldCat.org] [DOI] (I p)

David M J Lilley
How RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes.
Biochem Soc Trans: 2017, 45(3);683-691
[PubMed:28620029] [WorldCat.org] [DOI] (I p)

Jamie L Bingaman, Sixue Zhang, David R Stevens, Neela H Yennawar, Sharon Hammes-Schiffer, Philip C Bevilacqua
The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme.
Nat Chem Biol: 2017, 13(4);439-445
[PubMed:28192411] [WorldCat.org] [DOI] (I p)

Marcos de la Peña, Inmaculada García-Robles, Amelia Cervera
The Hammerhead Ribozyme: A Long History for a Short RNA.
Molecules: 2017, 22(1);
[PubMed:28054987] [WorldCat.org] [DOI] (I e)

Jennifer Gebetsberger, Ronald Micura
Unwinding the twister ribozyme: from structure to mechanism.
Wiley Interdiscip Rev RNA: 2017, 8(3);
[PubMed:27863022] [WorldCat.org] [DOI] (I p)

Michele Felletti, Jörg S Hartig
Ligand-dependent ribozymes.
Wiley Interdiscip Rev RNA: 2017, 8(2);
[PubMed:27687155] [WorldCat.org] [DOI] (I p)

Sabine Müller, Bettina Appel, Darko Balke, Robert Hieronymus, Claudia Nübel
Thirty-five years of research into ribozymes and nucleic acid catalysis: where do we stand today?
F1000Res: 2016, 5;
[PubMed:27408700] [WorldCat.org] [DOI] (P e)

Bradley P Klemm, Nancy Wu, Yu Chen, Xin Liu, Kipchumba J Kaitany, Michael J Howard, Carol A Fierke
The Diversity of Ribonuclease P: Protein and RNA Catalysts with Analogous Biological Functions.
Biomolecules: 2016, 6(2);
[PubMed:27187488] [WorldCat.org] [DOI] (I e)

Matthew W L Lau, Adrian R Ferré-D'Amaré
In vitro evolution of coenzyme-independent variants from the glmS ribozyme structural scaffold.
Methods: 2016, 106;76-81
[PubMed:27130889] [WorldCat.org] [DOI] (I p)

Randi M Jimenez, Julio A Polanco, Andrej Lupták
Chemistry and Biology of Self-Cleaving Ribozymes.
Trends Biochem Sci: 2015, 40(11);648-661
[PubMed:26481500] [WorldCat.org] [DOI] (I p)

Arati Ramesh, Wade C Winkler
Metabolite-binding ribozymes.
Biochim Biophys Acta: 2014, 1839(10);989-994
[PubMed:24769284] [WorldCat.org] [DOI] (P p)

Bo Gong, Daniel J Klein, Adrian R Ferré-D'Amaré, Paul R Carey
The glmS ribozyme tunes the catalytically critical pK(a) of its coenzyme glucosamine-6-phosphate.
J Am Chem Soc: 2011, 133(36);14188-91
[PubMed:21848325] [WorldCat.org] [DOI] (I p)

William H McClain, Lien B Lai, Venkat Gopalan
Trials, travails and triumphs: an account of RNA catalysis in RNase P.
J Mol Biol: 2010, 397(3);627-46
[PubMed:20100492] [WorldCat.org] [DOI] (I p)

William G Scott, Monika Martick, Young-In Chi
Structure and function of regulatory RNA elements: ribozymes that regulate gene expression.
Biochim Biophys Acta: 2009, 1789(9-10);634-41
[PubMed:19781673] [WorldCat.org] [DOI] (P p)

Jennifer A Collins, Irnov Irnov, Stephanie Baker, Wade C Winkler
Mechanism of mRNA destabilization by the glmS ribozyme.
Genes Dev: 2007, 21(24);3356-68
[PubMed:18079181] [WorldCat.org] [DOI] (P p)

Leif A Kirsebom
RNase P RNA mediated cleavage: substrate recognition and catalysis.
Biochimie: 2007, 89(10);1183-94
[PubMed:17624654] [WorldCat.org] [DOI] (P p)

Wade C Winkler, Ali Nahvi, Adam Roth, Jennifer A Collins, Ronald R Breaker
Control of gene expression by a natural metabolite-responsive ribozyme.
Nature: 2004, 428(6980);281-6
[PubMed:15029187] [WorldCat.org] [DOI] (I p)


Protein- or tRNA-controlled RNA switches


RNA thermometers

Satya Narayan, Mamta H Kombrabail, Sudipta Das, Himanshu Singh, Kandala V R Chary, Basuthkar J Rao, Guruswamy Krishnamoorthy
Site-specific fluorescence dynamics in an RNA 'thermometer' reveals the role of ribosome binding in its temperature-sensitive switch function.
Nucleic Acids Res: 2015, 43(1);493-503
[PubMed:25477380] [WorldCat.org] [DOI] (I p)


The RNA world and evolution


RNA modification


RNA degradation/ processing


Regulation by non-coding RNA


CRISPR/Cas: Science


CRISPR/Cas: Application