Cell wall degradation/ turnover

Parent categories	1. Cellular processes 1.1. Cell wall and cell division
Neighbouring categories	1.1.1. Cell wall synthesis 1.1.2. Cell shape 1.1.3. Cell wall degradation/ turnover 1.1.4. Capsule biosynthesis and degradation 1.1.5. Cell wall/ other 1.1.6. Membrane dynamics 1.1.7. Cell division
Related categories	MurR regulon WalR regulon
Overview on the categories (Excel file) All genes and their categories (Excel file)

Genes in this functional category

Endopeptidases

• cwlK
• cwlO
• cwlS
• lytE
• lytF
• lytH
• yqgT

Autolysis

• blyA
• cwlA
• cwlH

• cwlP
• cwlQ

• cwlT
• iseA
• lytA
• lytB
• lytC
• lytD

• lytG
• lytS
• lytT
• pbpE
• xepA
• xlyA
• xlyB
• yocH
• ysbB

Autolysis/ based on similarity

• ykvT
• ytkC

Utilization of cell wall components

• amiE
• gamA
• gamP
• murP
• murQ
• murR
• nagA
• nagB
• nagZ
• gamR

Additional genes

• yqiI

Important Reviews

Timothy K Lee, Kerwyn Casey Huang
The role of hydrolases in bacterial cell-wall growth.
Curr Opin Microbiol: 2013, 16(6);760-6
[PubMed:24035761] [WorldCat.org] [DOI] (I p)

Timna J Wyckoff, Jennifer A Taylor, Nina R Salama
Beyond growth: novel functions for bacterial cell wall hydrolases.
Trends Microbiol: 2012, 20(11);540-7
[PubMed:22944244] [WorldCat.org] [DOI] (I p)

Jan Reith, Christoph Mayer
Peptidoglycan turnover and recycling in Gram-positive bacteria.
Appl Microbiol Biotechnol: 2011, 92(1);1-11
[PubMed:21796380] [WorldCat.org] [DOI] (I p)

Sarah Dubrac, Paola Bisicchia, Kevin M Devine, Tarek Msadek
A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway.
Mol Microbiol: 2008, 70(6);1307-22
[PubMed:19019149] [WorldCat.org] [DOI] (I p)

Sarah Dubrac, Tarek Msadek
Tearing down the wall: peptidoglycan metabolism and the WalK/WalR (YycG/YycF) essential two-component system.
Adv Exp Med Biol: 2008, 631;214-28
[PubMed:18792692] [WorldCat.org] [DOI] (P p)

Waldemar Vollmer, Bernard Joris, Paulette Charlier, Simon Foster
Bacterial peptidoglycan (murein) hydrolases.
FEMS Microbiol Rev: 2008, 32(2);259-86
[PubMed:18266855] [WorldCat.org] [DOI] (P p)

Edie Scheurwater, Chris W Reid, Anthony J Clarke
Lytic transglycosylases: bacterial space-making autolysins.
Int J Biochem Cell Biol: 2008, 40(4);586-91
[PubMed:17468031] [WorldCat.org] [DOI] (P p)

Thomas J Smith, Steve A Blackman, Simon J Foster
Autolysins of Bacillus subtilis: multiple enzymes with multiple functions.
Microbiology (Reading): 2000, 146 ( Pt 2);249-262
[PubMed:10708363] [WorldCat.org] [DOI] (P p)