OpuBA

• Description: choline ABC transporter (ATP-binding protein)
  
  

Gene name	opuBA
Synonyms	proV
Essential	no
Product	choline ABC transporter (ATP-binding protein)
Function	compatible solute transport
Gene expression levels in SubtiExpress: opuBA
Interactions involving this protein in SubtInteract: OpuBA
Metabolic function and regulation of this protein in SubtiPathways: opuBA
MW, pI	42 kDa, 5.654
Gene length, protein length	1143 bp, 381 aa
Immediate neighbours	opuBB, yvaV
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, coping with hyper-osmotic stress, membrane proteins

This gene is a member of the following regulons

GbsR regulon, OpcR regulon, RemA regulon

The gene

Basic information

• Locus tag: BSU33730

Database entries

• BsubCyc: BSU33730

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s): OpuCA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • OpuBA-(OpuBB-OpuBC)-OpuBD PubMed

• Localization: associated to the membrane (via OpuBB-OpuBD) PubMed

Database entries

• BsubCyc: BSU33730

• Structure:

• UniProt: Q45460

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: opuBA-opuBB-opuBC-opuBD PubMed

• Expression browser: opuBA PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by salt stress PubMed
  • induced by choline (GbsR) PubMed

• Regulatory mechanism:
  • GbsR: transcription repression PubMed
  • OpcR: transcription repression PubMed
  • RemA: transcription activation PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 42 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 109 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 215 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 271 PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 161 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: