RpsD

• Description: ribosomal protein
  
  

Gene name	rpsD
Synonyms
Essential	yes PubMed
Product	ribosomal protein S4 (BS4)
Function	translation
Gene expression levels in SubtiExpress: rpsD
Interactions involving this protein in SubtInteract: RpsD
MW, pI	22 kDa, 10.243
Gene length, protein length	600 bp, 200 aa
Immediate neighbours	dgcP, tyrS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, essential genes, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU29660

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU29660

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ribosomal protein S4P family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU29660

• Structure: 1C06 (Geobacillus stearothermophilus)

• UniProt: P21466

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rpsD PubMed

• Expression browser: rpsD PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed
  • autorepression of rpsD expression upon binding of excess RpsD to a RNA switch in the untranslated region of the rpsD mRNA PubMed

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 8008 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 42285 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: