yvmA

168

exporter for the iron chelator pulcherriminic acid

Locus: BSU_35090

Molecular weight: 43.10 kDa

Isoelectric point: 9.69

Protein length: 403 aa

Gene length: 1212 bp

Function: biosynthesis of the extracellular iron chelator pulcherrimin

Product: pulcherriminic acid exporter

Essential: no

Synonyms: yvmA

Genomic Context

Hide small RNAsZoom:

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

Gene

Coordinates: 3,605,523  3,606,734

The protein

Protein family

• major facilitator superfamily (according to UniProt)
• TCR/Tet family (according to UniProt)

Structure

• O34307 (AlphaFold)

Localization

• cell membrane (according to UniProt)

Expression and Regulation

Operons

• Genes: pchR-yvmA

  Description: PubMed

  Regulation

  • induced by iron starvation PubMed

  Regulatory mechanism

  • CcpA: repression, PubMed; PchR auto-repression PubMed, in ccpA regulon
  • PchR: repression, in pchR regulon

Biological materials

Mutant

• BKE35090 (yvmA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAGTGTACACCGCCTTTT,  downstream forward: _UP4_TAAAAAAGCTGCCTTTGCGG
• BKK35090 (yvmA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAAAGTGTACACCGCCTTTT,  downstream forward: _UP4_TAAAAAAGCTGCCTTTGCGG

References

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