CotH

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  • Description: spore coat protein (inner), required for the assembly of several outer coat proteins

Gene name cotH
Synonyms ywrH
Essential no
Product spore coat protein (inner)
Function protection of CotU and CotC in the mother cell
Gene expression levels in SubtiExpress: cotH
MW, pI 42 kDa, 5.953
Gene length, protein length 1086 bp, 362 aa
Immediate neighbours cotB, cotG
Sequences Protein DNA DNA_with_flanks
Genetic context
CotH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CotH expression.png















Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU36060

Phenotypes of a mutant

  • overexpression of cotH suppresses the phenotypes of a cotE mutant PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: cotH family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References