BmrC

• Description: multidrug ABC transporter (ATP-binding protein), also involved in the signalling pathway to activate KinA at the onset of sporulation
  
  

Gene name	bmrC
Synonyms	yheI
Essential	no
Product	multidrug ABC transporter (ATP-binding protein)
Function	multiple antibiotic resistance
Gene expression levels in SubtiExpress: bmrC
Interactions involving this protein in SubtInteract: BmrC
MW, pI	64 kDa, 6.252
Gene length, protein length	1755 bp, 585 aa
Immediate neighbours	yheJ, bmrD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, resistance against toxins/ antibiotics, membrane proteins, sporulation proteins

The gene

Basic information

• Locus tag: BSU09710

Database entries

• BsubCyc: BSU09710

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: has both a membrane-spanning and an ATP-binding domain PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • BmrC-BmrD PubMed

• Localization: cell membrane PubMed

Database entries

• BsubCyc: BSU09710

• Structure:

• UniProt: O07550

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: bmrC PubMed

• Sigma factor:

• Regulation:
  • induced in response to antibiotics that target protein synthesis PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: