NonA

• Description: confers resistance to infection with phage SP10
  
  

Gene name	nonA
Synonyms
Essential	no
Product	inhibitor of NrdEF of phage SP10
Function	protection against phage SP10
Gene expression levels in SubtiExpress: nonA
MW, pI	8,465 kDa, 9.64
Gene length, protein length	219 bp, 72 aa
Immediate neighbours	yosP, nrdEB
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

SP-beta prophage, membrane proteins

The gene

Basic information

• Locus tag: none

Phenotypes of a mutant

• overexpression interferes with respiration (likely due to inhibition of NrdE) PubMed

Database entries

• BsubCyc: no entry

• DBTBS entry: no entry

• SubtiList entry: no entry

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • membrane PubMed

Database entries

• BsubCyc: no entry

• Structure:

• UniProt: no entry

• KEGG entry: no entry

• E.C. number:

Expression and regulation

• Operon: nonA PubMed

• Expression browser: nonA PubMed

• Sigma factor: Sig(ORF199-200) of phage SP10 PubMed

• Regulation:
  • expressed at late stage of phage SP10 infection PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Tatsuya Yamamoto, Nozomu Obana, Lii Mien Yee, Kei Asai, Nobuhiko Nomura, Kouji Nakamura
SP10 infectivity is aborted after bacteriophage SP10 infection induces nonA transcription on the prophage SPβ region of the Bacillus subtilis genome.
J Bacteriol: 2014, 196(3);693-706
[PubMed:24272782] [WorldCat.org] [DOI] (I p)