TagG

• Description: ABC transporter for teichoic acid translocation (permease)
  
  

Gene name	tagG
Synonyms
Essential	yes PubMed
Product	ABC transporter for teichoic acid translocation (permease)
Function	biosynthesis of teichoic acid
Gene expression levels in SubtiExpress: tagG
Interactions involving this protein in SubtInteract: TagG
Metabolic function and regulation of this protein in SubtiPathways: TagG
MW, pI	32 kDa, 9.565
Gene length, protein length	825 bp, 275 aa
Immediate neighbours	tagH, tagF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, ABC transporters, biosynthesis of cell wall components, essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU35710

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU35710

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC-2 integral membrane protein family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • TagG-TagH PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU35710

• Structure:

• UniProt: P42953

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: tagG PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 59 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 280 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Original publications

Kathrin Schirner, Laura K Stone, Suzanne Walker
ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers.
ACS Chem Biol: 2011, 6(5);407-12
[PubMed:21280653] [WorldCat.org] [DOI] (I p)

Alex Formstone, Rut Carballido-López, Philippe Noirot, Jeffery Errington, Dirk-Jan Scheffers
Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis.
J Bacteriol: 2008, 190(5);1812-21
[PubMed:18156271] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

V Lazarevic, D Karamata
The tagGH operon of Bacillus subtilis 168 encodes a two-component ABC transporter involved in the metabolism of two wall teichoic acids.
Mol Microbiol: 1995, 16(2);345-55
[PubMed:7565096] [WorldCat.org] [DOI] (P p)