RhaEW

• Description: bifunctional-rhamnulose-phosphate aldolase/L-lactate dehydrogenase
  
  

Gene name	yuxG
Synonyms	yulA
Essential	no
Product	bifunctional-rhamnulose-phosphate aldolase/L-lactate dehydrogenase
Function	utilizatio of rhamnose and rhamnogalacturonan (pectin)
Gene expression levels in SubtiExpress: rhaEW
MW, pI	75 kDa, 5.779
Gene length, protein length	2067 bp, 689 aa
Immediate neighbours	rhaR, tlpB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources

The gene

Basic information

• Locus tag: BSU31220

Database entries

• BsubCyc: BSU31220

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: rhamnulose-1-phosphate --> dihydroxyacetone-phosphate + L-lactate PubMed

• Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors: NAD⁺ PubMed

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU31220

• Structure:

• UniProt: P40747

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: rhaEW-rhaR-rhaB-rhaM-rhaA PubMed

• Expression browser: rhaEW PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Irina A Rodionova, Xiaoqing Li, Vera Thiel, Sergey Stolyar, Krista Stanton, James K Fredrickson, Donald A Bryant, Andrei L Osterman, Aaron A Best, Dmitry A Rodionov
Comparative genomics and functional analysis of rhamnose catabolic pathways and regulons in bacteria.
Front Microbiol: 2013, 4;407
[PubMed:24391637] [WorldCat.org] [DOI] (P e)

Pierre Nicolas, Ulrike Mäder, Etienne Dervyn, Tatiana Rochat, Aurélie Leduc, Nathalie Pigeonneau, Elena Bidnenko, Elodie Marchadier, Mark Hoebeke, Stéphane Aymerich, Dörte Becher, Paola Bisicchia, Eric Botella, Olivier Delumeau, Geoff Doherty, Emma L Denham, Mark J Fogg, Vincent Fromion, Anne Goelzer, Annette Hansen, Elisabeth Härtig, Colin R Harwood, Georg Homuth, Hanne Jarmer, Matthieu Jules, Edda Klipp, Ludovic Le Chat, François Lecointe, Peter Lewis, Wolfram Liebermeister, Anika March, Ruben A T Mars, Priyanka Nannapaneni, David Noone, Susanne Pohl, Bernd Rinn, Frank Rügheimer, Praveen K Sappa, Franck Samson, Marc Schaffer, Benno Schwikowski, Leif Steil, Jörg Stülke, Thomas Wiegert, Kevin M Devine, Anthony J Wilkinson, Jan Maarten van Dijl, Michael Hecker, Uwe Völker, Philippe Bessières, Philippe Noirot
Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis.
Science: 2012, 335(6072);1103-6
[PubMed:22383849] [WorldCat.org] [DOI] (I p)