QoxA

• Description: cytochrome aa3 quinol oxidase (subunit II)
  
  

Gene name	qoxA
Synonyms	ipa-37d
Essential	no
Product	cytochrome aa3 quinol oxidase (subunit II)
Function	respiration
Gene expression levels in SubtiExpress: qoxA
MW, pI	36 kDa, 4.796
Gene length, protein length	963 bp, 321 aa
Immediate neighbours	qoxB, ywzA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU38170

Phenotypes of a mutant

• inactivation of qoxA restores beta-lactam resistance in a sigM mutant PubMed

Database entries

• BsubCyc: BSU38170

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

• Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membranePubMed

Database entries

• BsubCyc: BSU38170

• Structure:

• UniProt: P34957

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: qoxA-qoxB-qoxC-qoxD PubMed

• Expression browser: qoxA PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 394 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 4774 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed