QoxA

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  • Description: cytochrome aa3 quinol oxidase (subunit II)

Gene name qoxA
Synonyms ipa-37d
Essential no
Product cytochrome aa3 quinol oxidase (subunit II)
Function respiration
Gene expression levels in SubtiExpress: qoxA
MW, pI 36 kDa, 4.796
Gene length, protein length 963 bp, 321 aa
Immediate neighbours qoxB, ywzA
Sequences Protein DNA DNA_with_flanks
Genetic context
QoxA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
QoxA expression.png















Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU38170

Phenotypes of a mutant

  • inactivation of qoxA restores beta-lactam resistance in a sigM mutant PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Ubiquinol-8 + O2 = Ubiquinone-8 + H2O (according to Swiss-Prot)
  • Protein family: cytochrome c oxidase subunit 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 394 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 4774 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed