Tgt

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  • Description: tRNA-guanine transglycosylase

Gene name tgt
Synonyms
Essential no
Product tRNA-guanine transglycosylase
Function tRNA modification
Gene expression levels in SubtiExpress: tgt
MW, pI 43 kDa, 6.149
Gene length, protein length 1143 bp, 381 aa
Immediate neighbours yrbF, queA
Sequences Protein DNA DNA_with_flanks
Genetic context
Tgt context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Tgt expression.png
























Categories containing this gene/protein

translation, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU27710

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: [tRNA]-guanine + queuine = [tRNA]-queuine + guanine (according to Swiss-Prot)
  • Protein family: queuine tRNA-ribosyltransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 258 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 1005 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References