PatA

• Description: aminotransferase
  
  

Gene name	patA
Synonyms	uat
Essential	yes PubMed
Product	aminotransferase
Function	biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: patA
Metabolic function and regulation of this protein in SubtiPathways: patA
MW, pI	43 kDa, 6.005
Gene length, protein length	1176 bp, 392 aa
Immediate neighbours	kinA, ykzT
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis/ acquisition of amino acids, Biosynthesis of cell wall components, essential genes

The gene

Basic information

• Locus tag: BSU14000

Phenotypes of a mutant

• essential PubMed

Database entries

• BsubCyc: BSU14000

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: N-acetyl-2-amino-6-ketopimelate --> N-acetyl-L,L-2,6-diaminopimelate PubMed

• Protein family: class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU14000

• Structure:

• UniProt: P16524

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: patA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 450 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1039 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed