RsbW

• Description: Anti-SigB, protein serine kinase, phosphorylates RsbV
  
  

Gene name	rsbW
Synonyms
Essential	no
Product	anti-SigB, protein serine kinase
Function	control of SigB activity
Gene expression levels in SubtiExpress: rsbW
Interactions involving this protein in SubtInteract: RsbW
Metabolic function and regulation of this protein in SubtiPathways: rsbW
MW, pI	17 kDa, 4.285
Gene length, protein length	480 bp, 160 aa
Immediate neighbours	rsbV, sigB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

protein modification, sigma factors and their control, general stress proteins (controlled by SigB)

This gene is a member of the following regulons

CcpA regulon, SigB regulon

The gene

Basic information

• Locus tag: BSU04720

Database entries

• BsubCyc: BSU04720

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + a protein = ADP + a phosphoprotein (according to Swiss-Prot)

• Protein family: anti-sigma-factor family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • RsbV-RsbW PubMed
  • SigB-RsbW PubMed

• Localization:

Database entries

• BsubCyc: BSU04720

• Structure:

• UniProt: P17904

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • rsbR-rsbS-rsbT-rsbU-rsbV-rsbW-sigB-rsbX PubMed
  • rsbV-rsbW-sigB-rsbX PubMed

• Expression browser: rsbW PubMed

• Sigma factor:
  • rsbR: SigA PubMed
  • rsbV: SigB PubMed

• Regulation:
  • rsbV: induced by stress (SigB) PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 699 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1277 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

• Bill Haldenwang, San Antonio, USA
• Chet Price, Davis, USA homepage