Ggt

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  • Description: gamma-glutamyltransferase

Gene name ggt
Synonyms pac
Essential no
Product gamma-glutamyltransferase
Function degradation of poly-glutamate capsules
Gene expression levels in SubtiExpress: ggt
MW, pI 64 kDa, 5.453
Gene length, protein length 1761 bp, 587 aa
Immediate neighbours yoeD, yofA
Sequences Protein DNA DNA_with_flanks
Genetic context
Ggt context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Ggt expression.png















Categories containing this gene/protein

capsule biosynthesis and degradation

This gene is a member of the following regulons

Efp-dependent proteins

The gene

Basic information

  • Locus tag: BSU18410

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl amino acid (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
    • strongly induced in response to glucose starvation in M9 medium PubMed
  • Regulatory mechanism:
  • Additional information:
    • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References