YfmE

• Description: iron/citrate ABC transporter (permease)
  
  

Gene name	yfmE
Synonyms
Essential	no
Product	iron/citrate ABC transporter (permease)
Function	iron uptake
Gene expression levels in SubtiExpress: yfmE
Interactions involving this protein in SubtInteract: YfmE
Metabolic function and regulation of this protein in SubtiPathways: YfmE
MW, pI	35 kDa, 10.061
Gene length, protein length	999 bp, 333 aa
Immediate neighbours	yfmF, yfmD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

• Locus tag: BSU07500

Database entries

• BsubCyc: BSU07500

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: FecCD subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YfmF-(YfmD-YfmE)-(YfmC-YhfQ) PubMed

• Localization:
  • cell membrane PubMed

Database entries

• BsubCyc: BSU07500

• Structure:

• UniProt: O34832

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yfmC-yfmD-yfmE-yfmF PubMed

• Expression browser: yfmE PubMed

• Sigma factor:

• Regulation:
  • induced upon iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Juliane Ollinger, Kyung-Bok Song, Haike Antelmann, Michael Hecker, John D Helmann
Role of the Fur regulon in iron transport in Bacillus subtilis.
J Bacteriol: 2006, 188(10);3664-73
[PubMed:16672620] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)