HtpG

• Description: class III heat-shock protein (molecular chaperone)
  
  

Gene name	htpG
Synonyms	yxbB
Essential	no
Product	class III heat-shock protein (molecular chaperone)
Function	chaperone
Gene expression levels in SubtiExpress: htpG
Metabolic function and regulation of this protein in SubtiPathways: htpG
MW, pI	72 kDa, 4.668
Gene length, protein length	1878 bp, 626 aa
Immediate neighbours	csbC, yxcA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

chaperones/ protein folding, heat shock proteins

The gene

Basic information

• Locus tag: BSU39820

Database entries

• BsubCyc: BSU39820

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: heat shock protein 90 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU39820

• Structure: 2IOQ (from Escherichia coli, 39% identity, 61% similarity) PubMed

• UniProt: P46208

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: htpG PubMed

• Expression browser: htpG PubMed

• Sigma factor: SigA PubMed

• Regulation: induced by high temperature PubMed

• Regulatory mechanism: unknown

• Additional information:

Biological materials

• Mutant: GP1159 (del cat) available in the Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Wolfgang Schumann, Bayreuth University, Germany Homepage