AtpF

• Description: ATP synthase, part of the Fo complex (subunit b)
  
  

Gene name	atpF
Synonyms
Essential	no
Product	ATP synthase (subunit b))
Function	ATP synthesis
Gene expression levels in SubtiExpress: atpF
Interactions involving this protein in SubtInteract: AtpF
MW, pI	19 kDa, 4.921
Gene length, protein length	510 bp, 170 aa
Immediate neighbours	atpH, atpE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ATP synthesis, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU36850

Database entries

• BsubCyc: BSU36850

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP synthesis see a video

• Protein family: ATPase B chain family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • A(1)-B(2)-C(12) - alpha(3)-beta(3)-gamma-delta-epsilon

• Localization:
  • membrane PubMed

Database entries

• BsubCyc: BSU36850

• Structure: see here an overview on ATPase structure

• UniProt: P37814

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: atpI-atpB-atpE-atpF-atpH-atpA-atpG-atpD-atpC PubMed

• Expression browser: atpF PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Original publications

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

M Santana, M S Ionescu, A Vertes, R Longin, F Kunst, A Danchin, P Glaser
Bacillus subtilis F0F1 ATPase: DNA sequence of the atp operon and characterization of atp mutants.
J Bacteriol: 1994, 176(22);6802-11
[PubMed:7961438] [WorldCat.org] [DOI] (P p)