TagB
- Description: putative CDP-glycerol:glycerol phosphate glycerophosphotransferase
| Gene name | tagB |
| Synonyms | |
| Essential | yes PubMed |
| Product | putative CDP-glycerol:glycerol phosphate glycerophosphotransferase |
| Function | biosynthesis of teichoic acid |
| Gene expression levels in SubtiExpress: tagB | |
| MW, pI | 44 kDa, 8.925 |
| Gene length, protein length | 1143 bp, 381 aa |
| Immediate neighbours | tagA, tagC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU35760
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU35760
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: adds a single glycerol phosphate residue to the non-reducing end of the undecaprenol-phosphate-linked N-acetylmannosamine-β(1,4)-N-acetylglucosamine-1-phosphate PubMed
- Protein family: CDP-glycerol glycerophosphotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane PubMed
Database entries
- BsubCyc: BSU35760
- Structure:
- UniProt: P27621
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alex Formstone, Rut Carballido-López, Philippe Noirot, Jeffery Errington, Dirk-Jan Scheffers
Localization and interactions of teichoic acid synthetic enzymes in Bacillus subtilis.
J Bacteriol: 2008, 190(5);1812-21
[PubMed:18156271]
[WorldCat.org]
[DOI]
(I p)
Amit P Bhavsar, Michael A D'Elia, Tiffany D Sahakian, Eric D Brown
The Amino terminus of Bacillus subtilis TagB possesses separable localization and functional properties.
J Bacteriol: 2007, 189(19);6816-23
[PubMed:17660278]
[WorldCat.org]
[DOI]
(P p)
Amit P Bhavsar, Ray Truant, Eric D Brown
The TagB protein in Bacillus subtilis 168 is an intracellular peripheral membrane protein that can incorporate glycerol phosphate onto a membrane-bound acceptor in vitro.
J Biol Chem: 2005, 280(44);36691-700
[PubMed:16150696]
[WorldCat.org]
[DOI]
(P p)
Amit P Bhavsar, Laura K Erdman, Jeffrey W Schertzer, Eric D Brown
Teichoic acid is an essential polymer in Bacillus subtilis that is functionally distinct from teichuronic acid.
J Bacteriol: 2004, 186(23);7865-73
[PubMed:15547257]
[WorldCat.org]
[DOI]
(P p)
Alistair Howell, Sarah Dubrac, Kasper Krogh Andersen, David Noone, Juliette Fert, Tarek Msadek, Kevin Devine
Genes controlled by the essential YycG/YycF two-component system of Bacillus subtilis revealed through a novel hybrid regulator approach.
Mol Microbiol: 2003, 49(6);1639-55
[PubMed:12950927]
[WorldCat.org]
[DOI]
(P p)
W Liu, S Eder, F M Hulett
Analysis of Bacillus subtilis tagAB and tagDEF expression during phosphate starvation identifies a repressor role for PhoP-P.
J Bacteriol: 1998, 180(3);753-8
[PubMed:9457886]
[WorldCat.org]
[DOI]
(P p)
C Mauël, A Bauduret, C Chervet, S Beggah, D Karamata
In Bacillus subtilis 168, teichoic acid of the cross-wall may be different from that of the cylinder: a hypothesis based on transcription analysis of tag genes.
Microbiology (Reading): 1995, 141 ( Pt 10);2379-89
[PubMed:7581998]
[WorldCat.org]
[DOI]
(P p)
C Mauël, M Young, A Monsutti-Grecescu, S A Marriott, D Karamata
Analysis of Bacillus subtilis tag gene expression using transcriptional fusions.
Microbiology (Reading): 1994, 140 ( Pt 9);2279-88
[PubMed:7952180]
[WorldCat.org]
[DOI]
(P p)
