LytB

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  • Description: modifier protein of major autolysin LytC

Gene name lytB
Synonyms cwbA
Essential no
Product modifier protein of major autolysin LytC
Function autolysis
Gene expression levels in SubtiExpress: lytB
MW, pI 76 kDa, 9.835
Gene length, protein length 2115 bp, 705 aa
Immediate neighbours lytC, lytA
Sequences Protein DNA DNA_with_flanks
Genetic context
LytB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LytB expression.png

























Categories containing this gene/protein

cell wall degradation/ turnover, membrane proteins

This gene is a member of the following regulons

SigD regulon, SlrR regulon, YvrHb regulon

The gene

Basic information

  • Locus tag: BSU35630

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Yunrong Chai, Thomas Norman, Roberto Kolter, Richard Losick
An epigenetic switch governing daughter cell separation in Bacillus subtilis.
Genes Dev: 2010, 24(8);754-65
[PubMed:20351052] [WorldCat.org] [DOI] (I p)

Masakuni Serizawa, Keisuke Kodama, Hiroki Yamamoto, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses.
Biosci Biotechnol Biochem: 2005, 69(11);2155-69
[PubMed:16306698] [WorldCat.org] [DOI] (P p)

P Margot, V Lazarevic, D Karamata
Effect of the SinR protein on the expression of the Bacillus subtilis 168 lytABC operon.
Microb Drug Resist: 1996, 2(1);119-21
[PubMed:9158733] [WorldCat.org] [DOI] (P p)

V Lazarevic, P Margot, B Soldo, D Karamata
Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier.
J Gen Microbiol: 1992, 138(9);1949-61
[PubMed:1357079] [WorldCat.org] [DOI] (P p)

A Kuroda, J Sekiguchi
Characterization of the Bacillus subtilis CwbA protein which stimulates cell wall lytic amidases.
FEMS Microbiol Lett: 1992, 74(1);109-13
[PubMed:1355454] [WorldCat.org] [DOI] (P p)