RluB

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  • Description: pseudouridine synthase

Gene name rluB
Synonyms ypuL
Essential no
Product pseudouridine synthase
Function 23S rRNA modification
Gene expression levels in SubtiExpress: rluB
MW, pI 25 kDa, 10.253
Gene length, protein length 687 bp, 229 aa
Immediate neighbours resA, spmB
Sequences Protein DNA DNA_with_flanks
Genetic context
RluB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
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Categories containing this gene/protein

translation, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU23160

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: rRNA uridine = rRNA pseudouridine (according to Swiss-Prot)
  • Protein family: pseudouridine synthase rsuA family (according to Swiss-Prot)
  • Paralogous protein(s): YtzF

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

L Niu, B G Lane, J Ofengand
Cloning and characterization of the 23S RNA pseudouridine 2633 synthase from Bacillus subtilis.
Biochemistry: 1999, 38(2);629-35
[PubMed:9888802] [WorldCat.org] [DOI] (P p)