PapB

• Description: Xaa-Pro amino-peptidase
  
  

Gene name	papB
Synonyms	ykvY
Essential	no
Product	Xaa-Pro amino-peptidase
Function	degradation of proline-containing peptides
Gene expression levels in SubtiExpress: papB
Metabolic function and regulation of this protein in SubtiPathways: papB
MW, pI	40 kDa, 5.171
Gene length, protein length	1089 bp, 363 aa
Immediate neighbours	zosA, ykvZ
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, coping with hyper-osmotic stress

The gene

Basic information

• Locus tag: BSU13860

Database entries

• BsubCyc: BSU13860

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M24B family (according to Swiss-Prot)

• Paralogous protein(s): PapA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU13860

• Structure: 3Q6D (B. anthracis Xaa-Pro dipeptidase, 35% identity, 55% similarity)

• UniProt: O31689

• KEGG entry: [2]

• E.C. number: 3.4.11.9

Expression and regulation

• Operon:

• Expression browser: papB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Adrienne Zaprasis, Jeanette Brill, Marietta Thüring, Guido Wünsche, Magnus Heun, Helena Barzantny, Tamara Hoffmann, Erhard Bremer
Osmoprotection of Bacillus subtilis through import and proteolysis of proline-containing peptides.
Appl Environ Microbiol: 2013, 79(2);576-87
[PubMed:23144141] [WorldCat.org] [DOI] (I p)